TY - BOOK AU - Neidle,Stephen TI - Cancer drug design and discovery SN - 9780123694485 PY - 2008/// CY - Boston PB - Academic Press KW - Antineoplastic agents KW - Development KW - Design N1 - Includes bibliographical references and index; Pt. I Basic Principles; Pt. II Methodology; Pt. III Drugs in the Clinic; Pt. IV New Agents; Pt. V The Reality of Cancer Drugs in the Clinic N2 - The ultimate source of information on the design of new anticancer agents, emphasising small molecules, this newest work covers recent notable successes resulting from the human genome and cancer genomics projects. These advances have provided information on targets involved in specific cancers that are leading to effective medicines for at least some of the common solid tumours; Unique sections explain the basic underlying principles of cancer drug development and provide a practical introduction to modern methods of drug design. Appealing to a broad audience, this is an excellent reference for translational researchers interested in cancer biology and medicine as well as students in pharmacy, pharmacology, or medicinal and biological chemistry, and clinicians taking oncology options ER -